Rat ATP1b1 (ATPase, Na+/K+ Transporting Beta 1 Polypeptide) Sandwich ELISA Kit Ready-To-Use

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Atp1b1
Gene ID:	25650
Uniprot ID:	AT1B1_RAT
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in the brain, liver, testes and anterior prostate (at protein level).
Post Translational Modifications	Glutathionylated. N-glycosylated.
Function	This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Plays a role in innate immunity by enhancing virus-triggered induction of interferons (IFNs) and interferon stimulated genes (ISGs). Mechanistically, enhances the ubiquitination of TRAF3 and TRAF6 as well as the phosphorylation of TAK1 and TBK1. Involved in cell adhesion and establishing epithelial cell polarity.
Protein Name	Sodium/Potassium-Transporting Atpase Subunit Beta-1 Sodium/Potassium-Dependent Atpase Subunit Beta-1
Database Links	Reactome: R-RNO-5578775 Reactome: -RNO-936837
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Apical Cell Membrane Sarcolemma Colocalizes With Obscn At The Intercalated Disk And Sarcolemma In Cardiomyocytes Localizes In Long Striations At The Level Of Z And M Lines
Alternative ELISA Names	Sodium/Potassium-Transporting Atpase Subunit Beta-1 ELISA kit Sodium/Potassium-Dependent Atpase Subunit Beta-1 ELISA kit Atp1b1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance