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> Anti-CLPS Antibody (4C277)

Anti-CLPS Antibody (4C277)

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Cat# NB-64-124571-100uL

Size : 100uL

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Anti-CLPS Antibody (4C277)

(Synonyms: colipase, pancreatic) Copy Product Info

Synonyms: colipase, pancreatic

Catalog No. TMAY-02612 Copy Product Info
Anti-CLPS Antibody (4C277) is a Mouse antibody targeting CLPS. Anti-CLPS Antibody (4C277) can be used in ELISA.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-CLPS Antibody (4C277) is a Mouse antibody targeting CLPS. Anti-CLPS Antibody (4C277) can be used in ELISA.
Synonymscolipase, pancreatic
Ig Type
Mouse IgG1
Clone
4C277
Reactivity
Human
Specificity
Human CLPS
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundColipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase can only be detected in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CLPS Protein (TMPY-02846)
Antigen Species
Human
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Related Tags: Anti-CLPS Antibody (4C277) chemical structure