| Short Description : | Rat monoclonal anti-Signal transducer CD24 for use in FC in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC |
| Host: | Rat |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | M1/69 |
| Isotype: | IgG2bk |
| Conjugation: | APC |
| Concentration: | 0.2 mg/mL |
| Formulation: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage Instruction: | Store between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
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| Tissue Specificity | In lymphoid, myeloid, and erythroid cells. |
| Post Translational Modifications | The identity of the N- and O-linked polysaccharides is not reported in PubMed:1530634. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc. |
| Function | May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
| Protein Name | Signal Transducer Cd24Lymphocyte Antigen 52Ly-52M1/69-J11d Heat Stable AntigenHsaNectadrinR13-AgX62 Heat Stable AntigenCd Antigen Cd24 |
| Database Links | |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Signal Transducer Cd24 antibodyAnti-Lymphocyte Antigen 52 antibodyAnti-Ly-52 antibodyAnti-M1/69-J11d Heat Stable Antigen antibodyAnti-Hsa antibodyAnti-Nectadrin antibodyAnti-R13-Ag antibodyAnti-X62 Heat Stable Antigen antibodyAnti-Cd Antigen Cd24 antibodyAnti-Cd24 antibodyAnti-Cd24a antibodyAnti-Ly-52 antibody |
Information sourced from Uniprot.org