General Information
| Short Description | This TKTL1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.062ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Widely expressed. Expressed in endothelial cells and in peripheral neurons (at protein level). Isoform 3: Not expressed in fetal neocortex. Isoform 4: Expressed in fetal neocortex. |
| Post Translational Modifications | |
| Function | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Isoform 4: During fetal neocortex development, may be essential to maintain the full number of basal radial glia (bRG). bRG are neural progenitor cells that undergo asymmetric divisions, generating a bRG (self-renewal) and a neuron, in contrast to basal intermediate progenitors (bIPs), which typically divide once to give rise to 2 neurons. bRG generate more cortical neurons over time than bIPs. |
| Protein Name | Transketolase-Like Protein 1Transketolase 2Tk 2Transketolase-Related Protein |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Transketolase-Like Protein 1 ELISA kitTransketolase 2 ELISA kitTk 2 ELISA kitTransketolase-Related Protein ELISA kitTKTL1 ELISA kitTKR ELISA kitTKT2 ELISA kit |
| output |
Information sourced from Uniprot.org