Anti-COMT Antibody (6P98)
Cat# NB-64-119984-50uL
Size : 50uL
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Anti-COMT Antibody (6P98)
(Synonyms: HEL-S-98n, catechol-O-methyltransferase) Copy Product InfoSynonyms: HEL-S-98n, catechol-O-methyltransferase
Catalog No. TMAH-00292 Copy Product Info
Anti-COMT Antibody (6P98) is an antibody targeting COMT. Anti-COMT Antibody (6P98) can be used in ELISA,IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
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| Description | Anti-COMT Antibody (6P98) is an antibody targeting COMT. Anti-COMT Antibody (6P98) can be used in ELISA,IHC,WB. |
| Synonyms | HEL-S-98n, catechol-O-methyltransferase |
| Ig Type | Rabbit IgG |
| Clone | 6P98 |
| Reactivity | Human |
| Verified Activity | 1. Western Blot -Positive WB detected in: 293 whole cell lysate, THP-1 whole cell lysate, HepG2 whole cell lysate -All lanes: COMT Antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 31, 25 kDa -Observed band size: 31 kDa 2. IHC image of TMAH-00292 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | ELISA IHC WB |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Isoform Soluble]: Cytoplasm.; [Isoform Membrane-bound]: Cell membrane; Single-pass type II membrane protein; Extracellular side. |
| Tissue Specificity | Brain, liver, placenta, lymphocytes and erythrocytes. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human COMT |
| Antigen Species | Human |
| Gene Name | COMT |
| Gene ID | 1312 |
| Uniprot ID | P21964 |
| Biology Area | Neuroscience, Cancer, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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