Size : 100mg
Phone : +1 850 650 7790
Synonyms: Lysophosphatidylcholines, Lyso-Lecithins (egg)
| Description | Lysophosphatidylcholines (Lyso-Lecithins (egg)) are orally active lipids that induce cell damage and apoptosis, and induce demyelination. Lysophosphatidylcholines play a role in mediating inflammation, fibrosis, and cancer, and can be used to study atherosclerosis. |
| In vitro | Lysophosphatidylcholines (3 μM, 10 μM, 30 μM, 100 μM; 24 hours) reduced HUVEC viability in a concentration-dependent manner[1]. |
| In vivo | Lysophosphatidylcholines (0.1 mg/kg, 1 mg/kg, 10 mg/kg, 20 mg/kg; oral) significantly protected albino ICR mice against cecal ligation and puncture (CLP)-induced lethality at a dose of 1 mg/kg[4]. |
| Synonyms | Lysophosphatidylcholines, Lyso-Lecithins (egg) |
| Cas No. | 9008-30-4 |
| Storage | Store at low temperature,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Chloroform:Methanol(2:1): Soluble DMSO: < 0.1 mg/mL (insoluble or slightly soluble) H2O: 50 mg/mL, Sonication is recommended.  Methanol: 15 mg/mL, Sonication is recommended. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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