Tamanho : 1g
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Synonyms: Sodium oleate, Oleic acid sodium salt, cis-9-Octadecenoic acid sodium salt
| Description | Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na+/K+ ATPase activator. |
| In vitro | Sodium oleate is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Sodium oleate prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Sodium oleate inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines[1]. |
| Synonyms | Sodium oleate, Oleic acid sodium salt, cis-9-Octadecenoic acid sodium salt |
| Molecular Weight | 304.44 |
| Formula | C18H33NaO2 |
| Cas No. | 143-19-1 |
| Smiles | [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O |
| Storage | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL (1.64 mM), Sonication is recommended. Ethanol: 1.5 mg/mL (4.93 mM), Sonication is recommended. H2O: 1.25 mg/mL (4.11 mM), Sonication is recommended.  DMSO: Insoluble |
Solution Preparation Table | |
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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