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Iron sucrose [8047-67-4]

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Referência NB-64-43820-100mg

Tamanho : 100mg

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Iron sucrose

(Synonyms: Sucroferric oxyhydroxide, Iron saccharate) Copy Product Info

Synonyms: Sucroferric oxyhydroxide, Iron saccharate

Catalog No. T8132 Copy Product Info

Purity: 99.97%

Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.

Cas No. 8047-67-4

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.97%

Appearance:Solid

Color:Brown

Product Introduction

Bioactivity

Description	Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.
Synonyms	Sucroferric oxyhydroxide, Iron saccharate
Cell Research	in vitro experiments on human peritoneal, the mesothelial effect of elemental iron (in conc. 0.0001-1 mg mL-1) present in Venofer on their viability, growth and synthesis of IL-6 was studied. Additionally we evaluated with a fluorescent probe (2',7'-dichlorodihydro-fluorescein diacatate) generation of reactive oxygen species in cells exposed to iron sucrose. We also measured accumulation of iron in the cytoplasm of mesothelial cells after their in vitro exposure to Venofer[1].

Chemical Properties

Molecular Weight	736.1
Formula	C₁₈H₂₄Fe₂O₂₄
Cas No.	8047-67-4
Smiles	[O-]C([C@H](O)[C@@H](O)[C@@H]([C@H](O)C([O-])=O)O)=O.[O-]C([C@H](O)[C@@H](O)[C@@H]([C@H](O)C([O-])=O)O)=O.[O-]C([C@H](O)[C@@H](O)[C@@H]([C@H](O)C([O-])=O)O)=O.[Fe+3].[Fe+3]
Relative Density.	no data available

Storage & Solubility Information

Storage

Keep away from direct sunlight,Keep away from moisture,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40.83 mg/mL (55.47 mM), Sonication is recommended.

H2O: 100 mg/mL (135.85 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 4.08 mg/mL (5.54 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.3585 mL	6.7926 mL	13.5851 mL	67.9256 mL
5 mM	0.2717 mL	1.3585 mL	2.7170 mL	13.5851 mL
10 mM	0.1359 mL	0.6793 mL	1.3585 mL	6.7926 mL
20 mM	0.0679 mL	0.3396 mL	0.6793 mL	3.3963 mL
50 mM	0.0272 mL	0.1359 mL	0.2717 mL	1.3585 mL

H2O

	1mg	5mg	10mg	50mg
100 mM	0.0136 mL	0.0679 mL	0.1359 mL	0.6793 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

VCAM-1safeReactiveOxygenSpeciesReactive Oxygen SpeciespregnancyNF-κBNADPHIron sucroseironIntravenousInhibitorinhibitIDAICAM-1hemoglobinH2O2ascorbateanemia

Related Tags: Iron sucrose chemical structure | Iron sucrose formula | Iron sucrose molecular weight