pro-Beta NGF Protein, Human, Recombinant
Referentie NB-64-53760-100ug
Formaat : 100ug
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pro-Beta NGF Protein, Human, Recombinant
(Synonyms: β-NGF, β-Nerve Growth Factor, pro-β NGF, pro-Beta NGF, NGFB, NGF, Beta-NGF, Beta-Nerve Growth Factor) Copy Product InfoSynonyms: β-NGF, β-Nerve Growth Factor, pro-β NGF, pro-Beta NGF, NGFB, NGF, Beta-NGF, Beta-Nerve Growth Factor
Catalog No. TMPJ-01468 Copy Product Info
Purity: 98%
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P01138 |
| Amino Acid | Glu19-Ala241 |
| Construction | Glu19-Ala241 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified)  |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 500 mM NaCl, 5%Trehalose, 5%Mannitol, 0.01%Tween 80, 1 mM EDTA, pH8.0. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | β-NGF, β-Nerve Growth Factor, pro-β NGF, pro-Beta NGF, NGFB, NGF, Beta-NGF, Beta-Nerve Growth Factor |
| Research Background | The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Keywords
pro-b NGFb-NGFb-Nerve Growth Factor
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Related Tags: pro-Beta NGF Protein, Human, Recombinant chemical structure
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