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Anti-GDNF Antibody (2K821)

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Formaat : 50uL

Telefoonnummer : +1 850 650 7790

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Telefoonnummer : +1 850 650 7790

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Synonyms:

Catalog No. TMAB-06414 Copy Product Info

Anti-GDNF Antibody (2K821) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (2K821) can be used in WB,FCM.

For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity

Description	Anti-GDNF Antibody (2K821) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (2K821) can be used in WB,FCM.
Ig Type	IgG
Clone	2K821
Reactivity	Human,Rat (predicted:Mouse)
Verified Activity	25 μg total protein per lane of various lysates (see on figure) probed with GDNF monoclonal antibody, unconjugated (TMAB-06414) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application	WB FCM
Recommended Dose	WB: 1:500-2000; FCM: 1:50-100
Antibody Type	Monoclonal
Host Species	Rabbit
Subcellular Localization	Secreted.
Tissue Specificity	In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
Construction	Recombinant Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research Background	Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Antigen Details

Immunogen	A synthesized peptide: human GDNF
Antigen Species	Human
Gene Name	GDNF
Gene ID	2668
Protein Name	Glial cell line-derived neurotrophic factor
Uniprot ID	P39905
Function	Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Chemical Properties

Molecular Weight	Theoretical: 24 kDa. Actual: 28 kDa.

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.

Related Tags: Anti-GDNF Antibody (2K821) molecular weight