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> Anti-MBP Antibody (8X293)

Anti-MBP Antibody (8X293)

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Referentie NB-64-118061-100uL

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Anti-MBP Antibody (8X293)

(Synonyms: Shi, Myelin basic protein, Myelin A1 protein, Mbp) Copy Product Info

Synonyms: Shi, Myelin basic protein, Myelin A1 protein, Mbp

Catalog No. TMAC-02715 Copy Product Info
Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Description
Anti-MBP Antibody (8X293) is a Rabbit antibody targeting MBP. Anti-MBP Antibody (8X293) can be used in IHC,WB.
SynonymsShi, Myelin basic protein, Myelin A1 protein, Mbp
Ig Type
IgG
Clone
8X293
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Myelin Basic Protein antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Myelin Basic Protein antibody. Counter stained with hematoxylin.
Anti-MBP Antibody (8X293),Anti-MBP Antibody (8X293)
Application
IHC
WB
Recommended Dose
WB: 1:1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMyelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosphorylation during myelinogenesis and in the demyelinating disease multiple sclerosis. MBP phosphorylation is regulated by high-frequency stimulation but not low-frequency stimulation of the alveus, the myelinated output fibers of the hippocampus. It is proposed that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
P02686
Chemical Properties
Molecular WeightTheoretical: 33/21/19 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Keywords

MyelinA1 protein
Related Tags: Anti-MBP Antibody (8X293) molecular weight