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Lactose [63-42-3]

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Referentie NB-64-00760-1mL

Formaat : 1mLx10mM(inDMSO)

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Lactose

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Synonyms:

Catalog No. T0586 Copy Product Info

Purity: 99.63%

Lactose is a disaccharide derived from galactose and glucose that is found in milk.

Cas No. 63-42-3

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.63%

Appearance:Solid

Color:White

Product Introduction

Lactose AI Summary

Lactose shows a binding affinity to human Gal-1, inhibiting Gal-1 from binding to immobilized asialofetuin and lactose with an IC50 value of 4670 μM. The dissociation constant (Kd) is 187 μM. Thermodynamic analysis reveals changes in enthalpy (ΔH) of -45.2 kJ/mol, entropy (ΔS) of -80.2 J/mol.K, and a -TΔS value of 23.9 kJ/mol, resulting in a Gibbs free energy change (ΔG) of -21.3 kJ/mol..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Lactose is a disaccharide derived from galactose and glucose that is found in milk.

Chemical Properties

Molecular Weight	342.30
Formula	C₁₂H₂₂O₁₁
Cas No.	63-42-3
Smiles	O([C@@H]([C@@H]([C@H](C=O)O)O)[C@@H](CO)O)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Relative Density.	1.5300 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 59 mg/mL (172.36 mM), Sonication is recommended.

H2O: 6.25 mg/mL (18.26 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.84 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9214 mL	14.6071 mL	29.2141 mL	146.0707 mL
5 mM	0.5843 mL	2.9214 mL	5.8428 mL	29.2141 mL
10 mM	0.2921 mL	1.4607 mL	2.9214 mL	14.6071 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1461 mL	0.7304 mL	1.4607 mL	7.3035 mL
50 mM	0.0584 mL	0.2921 mL	0.5843 mL	2.9214 mL
100 mM	0.0292 mL	0.1461 mL	0.2921 mL	1.4607 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

LactoseInhibitorinhibitEndogenousMetaboliteEndogenous Metabolite

Related Tags: Lactose chemical structure | Lactose formula | Lactose molecular weight

Lactose [63-42-3]

Referentie NB-64-00760-1mL

Neem contact op met een lokale distributeur :

Neem contact op met een lokale distributeur :

Lactose

Product Introduction

Calculator

In Vivo Formulation Calculator (Clear solution)

Dose Conversion

Keywords

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