Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.

L-GLUCOSE [921-60-8]

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Referentie NB-64-29545-500mg

Formaat : 500mg

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L-GLUCOSE

(Synonyms: L-(-)-Glucose) Copy Product Info

Synonyms: L-(-)-Glucose

Catalog No. T5113 Copy Product Info

Purity: 99.94%

L-Glucose (L-(-)-Glucose), an enantiomer of D-glucose, is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.

Cas No. 921-60-8

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.94%

Appearance:Solid

Color:White

Product Introduction

L-GLUCOSE AI Summary

L-GLUCOSE exhibits acceptor substrate specificity toward Fucosyltransferase for the galactosides of GlcNAc with beta 1,3 or beta 1,4-linkages, with a relative activity of 3.0. It was tested for inhibition of Human acrosin by aldohexoses and showed 0.0% inhibition. Additionally, L-GLUCOSE demonstrated bioactivity as an inhibitor of Polymerase Kappa with a potency of 15003.0 nM in the "qHTS for Inhibitors of Polymerase Kappa" assay..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	L-Glucose (L-(-)-Glucose), an enantiomer of D-glucose, is not bioavailable to cells as an energy source because it cannot be phosphorylated by hexokinase.
Synonyms	L-(-)-Glucose

Chemical Properties

Molecular Weight	180.16
Formula	C₆H₁₂O₆
Cas No.	921-60-8
Smiles	OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)C=O
Relative Density.	1.732 g/cm3

Storage & Solubility Information

Storage

Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 142.8 mg/mL (792.63 mM), Sonication is recommended.

H2O: 50 mg/mL (277.53 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 10 mg/mL (55.51 mM), Solution.

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (11.1 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5506 mL	27.7531 mL	55.5062 mL	277.5311 mL
5 mM	1.1101 mL	5.5506 mL	11.1012 mL	55.5062 mL
10 mM	0.5551 mL	2.7753 mL	5.5506 mL	27.7531 mL
20 mM	0.2775 mL	1.3877 mL	2.7753 mL	13.8766 mL
50 mM	0.1110 mL	0.5551 mL	1.1101 mL	5.5506 mL
100 mM	0.0555 mL	0.2775 mL	0.5551 mL	2.7753 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

L-GlucoseLGLUCOSEL GLUCOSEInhibitorinhibitenantiomerD-glucose

Related Tags: L-GLUCOSE chemical structure | L-GLUCOSE formula | L-GLUCOSE molecular weight