General Information
| Short Description | Mouse monoclonal anti-Histone H3.1 and Histone H3.2 and Histone H3.3 for use in WB, IHC, IF and IP in Human, Mouse, Rat, Yeast and A.thaliana samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/IP |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat/Yeast/A.thaliana |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1G1 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:2000-5000IF 1:100-500IP 1:200IHC 1:50-300 |
| Formulation | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | < |
| Immunogen | Recombinant Protein of Histone H3 |
| Specificity | The antibody detects endogenous Histone H3 protein. |
Additional Info
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H3.1Histone H3/AHistone H3/BHistone H3/CHistone H3/DHistone H3/FHistone H3/HHistone H3/IHistone H3/JHistone H3/KHistone H3/L |
| Database Links | |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H3.1 antibodyAnti-Histone H3/A antibodyAnti-Histone H3/B antibodyAnti-Histone H3/C antibodyAnti-Histone H3/D antibodyAnti-Histone H3/F antibodyAnti-Histone H3/H antibodyAnti-Histone H3/I antibodyAnti-Histone H3/J antibodyAnti-Histone H3/K antibodyAnti-Histone H3/L antibodyAnti-H3C1 antibodyAnti-H3FA antibodyAnti-HIST1H3A.H3C2 antibodyAnti-H3FL antibodyAnti-HIST1H3B.H3C3 antibodyAnti-H3FC antibodyAnti-HIST1H3C.H3C4 antibodyAnti-H3FB antibodyAnti-HIST1H3D.H3C6 antibodyAnti-H3FD antibodyAnti-HIST1H3E.H3C7 antibodyAnti-H3FI antibodyAnti-HIST1H3F.H3C8 antibodyAnti-H3FH antibodyAnti-HIST1H3G.H3C10 antibodyAnti-H3FK antibodyAnti-HIST1H3H.H3C11 antibodyAnti-H3FF antibodyAnti-HIST1H3I.H3C12 antibodyAnti-H3FJ antibodyAnti-HIST1H3J antibody |
Information sourced from Uniprot.org