Reagentia en instrumenten voor immunologie, celbiologie en moleculaire biologie.

Ammonium formate [540-69-2]

Afdrukken

Referentie NB-64-29724-10g

Formaat : 10g

Neem contact op met een lokale distributeur :

Telefoonnummer : +1 850 650 7790

Meer informatie aanvragen

Neem contact op met een lokale distributeur :

Telefoonnummer : +1 850 650 7790

Remove All

Ammonium formate

(Synonyms: Formic acid ammonium salt) Copy Product Info

Synonyms: Formic acid ammonium salt

Catalog No. T5300 Copy Product Info

Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.

Cas No. 540-69-2

For research use only—not for human use. No sales to individuals. Use as intended only.

Select Batch

Purity:≥95%

Appearance:Viscous

Color:White

Product Introduction

Bioactivity

Description	Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity, the terminal electron acceptor of the electron transport chain. Cell death from cytochrome oxidase inhibition by formate is believed to result partly from depletion of ATP, reducing energy concentrations so that essential cell functions cannot be maintained. Furthermore, inhibition of cytochrome oxidase by formate may also cause cell death by increased production of cytotoxic reactive oxygen species (ROS) secondary to the blockade of the electron transport chain.
Synonyms	Formic acid ammonium salt

Chemical Properties

Molecular Weight	63.06
Formula	CH₅NO₂
Cas No.	540-69-2
Smiles	[NH4+].[O-]C=O
Relative Density.	1.26 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (951.47 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (79.29 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	15.8579 mL	79.2896 mL	158.5791 mL	792.8957 mL
5 mM	3.1716 mL	15.8579 mL	31.7158 mL	158.5791 mL
10 mM	1.5858 mL	7.9290 mL	15.8579 mL	79.2896 mL
20 mM	0.7929 mL	3.9645 mL	7.9290 mL	39.6448 mL
50 mM	0.3172 mL	1.5858 mL	3.1716 mL	15.8579 mL
100 mM	0.1586 mL	0.7929 mL	1.5858 mL	7.9290 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

Formic acid ammoniumAmmonium formate

Related Tags: Ammonium formate chemical structure | Ammonium formate formula | Ammonium formate molecular weight

Ammonium formate [540-69-2]

Referentie NB-64-29724-10g

Neem contact op met een lokale distributeur :

Neem contact op met een lokale distributeur :

Ammonium formate

Product Introduction

Calculator

In Vivo Formulation Calculator (Clear solution)

Dose Conversion

Keywords

Misschien heeft u ook interesse in de volgende producten: