Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare

PG 01037 dihydrochloride [675599-62-9]

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Cat# NB-64-12400-2mg

Size : 2mg

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PG 01037 dihydrochloride

(Synonyms: PG-01037 2HCl) Copy Product Info

Synonyms: PG-01037 2HCl

Catalog No. T23143 Copy Product Info

Purity: 99.89%

PG 01037 dihydrochloride (PG-01037 2HCl) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.

Cas No. 675599-62-9

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.89%

Appearance:Solid

Color:White

Product Introduction

Bioactivity

Description	PG 01037 dihydrochloride (PG-01037 2HCl) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.
Targets & IC50	D3 receptor:0.7 nM (Ki)
Synonyms	PG-01037 2HCl

Chemical Properties

Molecular Weight	554.34
Formula	C₂₆H₂₈Cl₄N₄O
Cas No.	675599-62-9
Smiles	ClC1=C(N2CCN(CC2)C/C=C/CNC(C3=CC=C(C4=CC=CC=N4)C=C3)=O)C=CC=C1Cl.Cl.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (45.1 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (3.61 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8039 mL	9.0197 mL	18.0395 mL	90.1974 mL
5 mM	0.3608 mL	1.8039 mL	3.6079 mL	18.0395 mL
10 mM	0.1804 mL	0.9020 mL	1.8039 mL	9.0197 mL
20 mM	0.0902 mL	0.4510 mL	0.9020 mL	4.5099 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

PG-01037 DihydrochloridePG01037 DihydrochloridePG-01037PG01037PG 01037 DihydrochloridePG 01037DopamineReceptorDopamine ReceptorD3 receptor

Related Tags: PG 01037 dihydrochloride chemical structure | PG 01037 dihydrochloride formula | PG 01037 dihydrochloride molecular weight