NB-21-26333 | Nipah virus(HeV) -Fusion glycoprotein F0 recombinant

Host species:: Mammalian cells
Origin species:: Nipah virus(HeV)
Uniprot ID:: Q9IH63
Molecular weight:: 57.71 kDa

Ile27–Ser493 His

Datasheet

Specifications Nipah virus(HeV) -Fusion glycoprotein F0 recombinant protein

Product name	Nipah virus(HeV) -Fusion glycoprotein F0 recombinant protein
Uniprot ID	Q9IH63
Origin species	Nipah virus(HeV)
Expression system	Eukaryotic expression
Raw Antigen Sequence	ILHYEKLSKIGLVKGVTRKYKIKSNPLTKDIVIKMIPNVSNMSQCTGSVMENYKTRLNGILTPIKGALEIYKNNTHDLVGDVRLAGVIMAGVAIGIATAAQITAGVALYEAMKNADNINKLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINTNLVPTIDKISCKQTELSLDLALSKYLSDLLFVFGPNLQDPVSNSMTIQAISQAFGGNYETLLRTLGYATEDFDDLLESDSITGQIIYVDLSSYYIIVRVYFPILTEIQQAYIQELLPVSFNNDNSEWISIVPNFILVRNTLISNIEIGFCLITKRSVICNQDYATPMTNNMRECLTGSTEKCPRELVVSSHVPRFALSNGVLFANCISVTCQCQTTGRAISQSGEQTLLMIDNTTCPTAVLGNVIISLGKYLGSVNYNSEGIAIGPPVFTDKVDISSQISSMNQSLQQSKDYIKEAQRLLDTVNPSLISMLS
Molecular weight	57.71 kDa
Protein delivered with Tag?	C-Terminal His Tag
Purity estimated	>85% by SDS-PAGE
Buffer	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Delivery condition	Dry Ice
Delivery lead time in business days	3-5 days if in stock; 3-5 weeks if production needed
Storage condition	4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Brand	ProteoGenix
Host species	Mammalian cells
Fragment Type	Ile27-Ser493
Aliases /Synonyms	Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Nipah Virus (NiV) / Hendra Virus (HeV)
Reference	PX-P6240
Note	For research use only.
Molecular Constructor	Ile27–Ser493 His

Description

Nipah Virus (HeV) Structure

Nipah virus (HeV) is a negative-sense, single-stranded RNA virus belonging to the family Paramyxoviridae. It is composed of a nucleocapsid core surrounded by a lipid envelope and a matrix protein. Its genome is 15,000 nucleotides in length, and it encodes six structural proteins and four non-structural proteins.

Nipah Virus (HeV) Activity

The activity of the Nipah virus (HeV) is mediated by its structural proteins. The F and G glycoproteins form the virus’ fusion complex, allowing it to enter host cells and fuse with the host cell membrane. The matrix protein M is involved in viral assembly and budding from the host cell. The nucleocapsid protein N is involved in the formation of the viral ribonucleoprotein complex.

Nipah Virus (HeV) Drug Target

The F fusion glycoprotein F0 is a potential drug target for Nipah virus (HeV). This protein is essential for the virus’ entry into host cells and is a promising target for vaccine and therapeutic strategies. Inhibition of the F0 glycoprotein could prevent the virus from entering host cells, thus preventing infection.

Documents

Datasheet

3D Representation

Publications

Bezeljak U, Jerman A, Kobal T, et al. Purification and immunogenicity of Nipah virus-like particles from insect cells. BMC Biotechnology. 2025 Dec;26(1):14. DOI: 10.1186/s12896-025-01095-w. PMID: 41476213; PMCID: PMC12866483 https://doi.org/10.1186/s12896-025-01095-w
Stewart, M., Bone, P., Bacon, A. et al. Protective immunity in hamsters from an oral Nipah vaccine correlates with pseudovirus neutralising antibody titre. Sci Rep (2026).https://doi.org/10.1038/s41598-026-40205-2

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Nipah virus(HeV) -Fusion glycoprotein F0 recombinant protein

Cat# NB-21-26333

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