Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare

N-Nitroso Sarcosine [13256-22-9]

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Cat# NB-64-24110-100mg

Size : 100mg

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N-Nitroso Sarcosine

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Synonyms:

Catalog No. T36414 Copy Product Info

N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2

Cas No. 13256-22-9

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity

Description	N-Nitroso sarcosine is a carcinogen and nitrosation product of sarcosine that has been found in cured meat products.1,2
In vivo	In vivo, N-nitroso sarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.2

Chemical Properties

Molecular Weight	118.0913
Formula	C₃H₆N₂O₃
Cas No.	13256-22-9
Smiles	CN(CC(O)=O)N=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (84.68 mM), Sonication is recommended.

DMF: 15 mg/mL (127.02 mM), Sonication is recommended.

Ethanol: 30 mg/mL (254.04 mM), Sonication is recommended.

PBS (pH 7.2): 5 mg/mL (42.34 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
1 mM	8.4680 mL	42.3401 mL	84.6802 mL	423.4012 mL
5 mM	1.6936 mL	8.4680 mL	16.9360 mL	84.6802 mL
10 mM	0.8468 mL	4.2340 mL	8.4680 mL	42.3401 mL
20 mM	0.4234 mL	2.1170 mL	4.2340 mL	21.1701 mL

DMSO/DMF/Ethanol

	1mg	5mg	10mg	50mg
50 mM	0.1694 mL	0.8468 mL	1.6936 mL	8.4680 mL

DMF/Ethanol

	1mg	5mg	10mg	50mg
100 mM	0.0847 mL	0.4234 mL	0.8468 mL	4.2340 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

N-Nitroso SarcosineNNitroso SarcosineN Nitroso Sarcosine

Related Tags: N-Nitroso Sarcosine chemical structure | N-Nitroso Sarcosine in vivo | N-Nitroso Sarcosine formula | N-Nitroso Sarcosine molecular weight