Reagenti e strumenti per immunologia, biologia cellulare e biologia molecolare

Imipramine N-oxide [6829-98-7]

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Cat# NB-64-41541-1ml

Size : 1mLx10mM(inDMSO)

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Telefono : +1 850 650 7790

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Contatta il distributore locale :

Telefono : +1 850 650 7790

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Imipramine N-oxide

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Synonyms:

Catalog No. T74205 Copy Product Info

Purity: 99.80%

Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression. Imipramine N-oxide can be reduced to imipramine in vitro within rat tissue homogenates or blood.

Cas No. 6829-98-7

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.80%

Appearance:Solid

Color:White

Product Introduction

Bioactivity

Description	Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression. Imipramine N-oxide can be reduced to imipramine in vitro within rat tissue homogenates or blood.

Chemical Properties

Molecular Weight	296.41
Formula	C₁₉H₂₄N₂O
Cas No.	6829-98-7
Smiles	O=N(C)(C)CCCN1C=2C=CC=CC2CCC=3C=CC=CC31

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (269.9 mM)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.13 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3737 mL	16.8685 mL	33.7371 mL	168.6853 mL
5 mM	0.6747 mL	3.3737 mL	6.7474 mL	33.7371 mL
10 mM	0.3374 mL	1.6869 mL	3.3737 mL	16.8685 mL
20 mM	0.1687 mL	0.8434 mL	1.6869 mL	8.4343 mL
50 mM	0.0675 mL	0.3374 mL	0.6747 mL	3.3737 mL
100 mM	0.0337 mL	0.1687 mL	0.3374 mL	1.6869 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Related Tags: Imipramine N-oxide chemical structure | Imipramine N-oxide formula | Imipramine N-oxide molecular weight