Size : 25g
Telefono : +1 850 650 7790
Synonyms: Arabic gum
| Description | Gum arabic is an orally active natural branched polymer primarily composed of a mixture of polysaccharides and glycoproteins. It exhibits biocompatibility, hydrophilicity, and antimicrobial properties, commonly used in biomaterials, stabilizers, emulsifiers, etc. Gum Arabic demonstrates hepatoprotective, cardiovascular protective, anti-obesity, and upregulation of cell maturation marker expression activities. |
| In vitro | Gum arabic (0.5%, 10 min, 60 min, and 120 min) can significantly promote the phosphorylation of ERK1/2 in mouse bone marrow-derived dendritic cells (DCs) [1]. |
| In vivo | Oral administration of Gum arabic (100 g/L for 5 consecutive days) through drinking water significantly reduced acetaminophen-induced hepatotoxicity in male Swiss albino mice [2]. Gum arabic (10% w/w, administered orally via diet for 12 weeks) inhibited high-fat diet-induced obesity in mice, primarily by reducing body weight, decreasing visceral adipose tissue (VAT) mass, lowering blood glucose and plasma lipid (total cholesterol, LDL, VLDL) levels, and regulating hepatic lipid metabolism-related genes [3]. |
| Synonyms | Arabic gum |
| Cas No. | 9000-01-5 |
| Relative Density. | 1.35 g/cm3 |
| Storage | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: ≥ 40 mg/mL, Sonication is recommended. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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