Size : 1mLx10mM(inDMSO)
Telefono : +1 850 650 7790
Synonyms: NSC-34858, NSC34858, NSC 34858, EI-38,555, EI38,555, EI 38,555
| Description | Chlormequat chloride (EI 38,555), a plant growth regulator, is widely applied in agriculture because it can promote sturdier growth of the crops. |
| In vitro | Chlormequat chloride at 150μg/ml (0.93mM) retarded the rat embryo growth without causing significant morphological malformations and at 500μg/ml (3.1mM) caused both retardation and morphological malformation of the embryos. However, the proliferation and differentiation of limb bud cells were not affected by chlormequat chloride at as high as up to 1000μg/ml (6.2mM) applied. This concentration of chlormequat chloride did not affect the cell viability as examined by 3T3 fibroblast cytotoxicity test either, suggesting that cellular toxicity may not play a role in chlormequat induced inhibition of rat embryo growth[1]. |
| In vivo | Chlormequat chloride(5 μg/mL) increased the embryonic growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels both in vitro and in vivo compared with the control ones[1]. |
| Synonyms | NSC-34858, NSC34858, NSC 34858, EI-38,555, EI38,555, EI 38,555 |
| Molecular Weight | 158.07 |
| Formula | C5H13Cl2N |
| Cas No. | 999-81-5 |
| Smiles | C[N+](C)(C)CCCl.[Cl-] |
| Relative Density. | 1.2228 g/cm3 (Estimated) |
| Storage | Store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 65 mg/mL (411.21 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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