Ampicillin sodium [69-52-3]
Cat# NB-64-34444-5g
Size : 5g
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Ampicillin sodium (Synonyms: Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral)
Catalog No. T6386 Copy Product Info
Purity: 99.26%
Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Ampicillin sodium
Copy Product InfoSynonyms Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral
Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Cas No. 69-52-3
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Purity:99.26%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria. |
| Targets&IC50 | enzyme transpeptidase:1.8 µg/mL, transporter:9.9 mM (Ki), carnitine/carnitine antiport:7.6 mM, HEK293 cells:> 100 μM (CC50) |
| In vitro | METHODS: After treating porcine Escherichia coli with Ampicillin sodium (0.1, 1, 2.5, 5, 10 μg/mL), E.M.B was observed. The number of viable Escherichia coli on the culture medium. RESULTS: Ampicillin inhibited the growth of porcine Escherichia coli in a dose-dependent manner. The effective inhibitory concentration of Ampicillin is 2.5 μg/mL. [1] |
| In vivo | METHODS: To study the antibacterial effect of Ampicillin sodium, Ampicillin (0.2 mL/20 g) was orally or subcutaneously injected into mice. RESULTS: The efficacy of Ampicillin in treating most infections is significantly better than that of Epicillin and Amoxycillin. [2] METHODS: To study the neuroprotective effect of Ampicillin sodium, Ampicillin sodium (200 mg/kg) was intraperitoneally injected into a mouse model of transient anterior cerebral ischemia. RESULTS: Ampicillin sodium can significantly reduce hippocampal cell death, lower the activity of matrix metalloproteinases (MMP), and increase the expression of glutamate transporter-1 (GLT-1). [3] |
| Synonyms | Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral |
| Molecular Weight | 371.39 |
| Formula | C16H18N3NaO4S |
| Cas No. | 69-52-3 |
| Smiles | [Na+].CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C([O-])=O |
| Relative Density. | no data available |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 68 mg/mL (183.1 mM), Sonication is recommended. Ethanol: 69 mg/mL (185.79 mM), Sonication is recommended. DMSO: 270 mg/mL (727 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (13.46 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/Ethanol/DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||