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Tetrazole [27988-97-2]

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Référence NB-64-44803-10mg

Conditionnement : 10mg

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Tetrazole

(Synonyms: 1H-TETRAZOLE) Copy Product Info

Synonyms: 1H-TETRAZOLE

Catalog No. T8520 Copy Product Info

Purity: 99.66%

Tetrazole (1H-TETRAZOLE) is the bioisoster of carboxylic acid, possess considerable antibacterial property.

Cas No. 27988-97-2

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.66%

Product Introduction

Tetrazole AI Summary

Tetrazole displays bioactivity related to its dissociation constant, specifically a pKa value. It has a pKa of 4.79 determined by spectrophotometric analysis at a pH range of 2 to 3, although a different analysis provided a pKa of -3.0..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Tetrazole (1H-TETRAZOLE) is the bioisoster of carboxylic acid, possess considerable antibacterial property.
Synonyms	1H-TETRAZOLE

Chemical Properties

Molecular Weight	70.05
Formula	CH₂N₄
Cas No.	27988-97-2
Smiles	c1nn[nH]n1
Relative Density.	0.798 g/mL at 20°C

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 37.5 mg/mL (535.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	14.2755 mL	71.3776 mL	142.7552 mL	713.7759 mL
5 mM	2.8551 mL	14.2755 mL	28.5510 mL	142.7552 mL
10 mM	1.4276 mL	7.1378 mL	14.2755 mL	71.3776 mL
20 mM	0.7138 mL	3.5689 mL	7.1378 mL	35.6888 mL
50 mM	0.2855 mL	1.4276 mL	2.8551 mL	14.2755 mL
100 mM	0.1428 mL	0.7138 mL	1.4276 mL	7.1378 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

TetrazoleBacterial

Related Tags: Tetrazole chemical structure | Tetrazole formula | Tetrazole molecular weight