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Menthol [1490-04-6]

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Référence NB-64-30126-1mL

Conditionnement : 1mLx10mM(inDMSO)

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Menthol

(Synonyms: DL-Menthol) Copy Product Info

Synonyms: DL-Menthol

Catalog No. T5723 Copy Product Info

Purity: 99.88%

Menthol (DL-Menthol) is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.

Cas No. 1490-04-6

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.88%

Appearance:solid

Color:White

Product Introduction

Bioactivity

Description	Menthol (DL-Menthol) is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.
In vivo	High levels of the major DL-Menthol metabolite, menthol-glucuronide, was observed in the urine of smokers of either menthol or non-menthol cigarettes. The fact that a significant inverse correlation was observed between the levels of urinary menthol-glucuronide and NNAL-N-glucuronide, a major detoxification metabolite of the tobacco carcinogen, NNK, suggests that menthol may be inhibiting the clearance of this important tobacco carcinogen.
Synonyms	DL-Menthol

Chemical Properties

Molecular Weight	156.26
Formula	C₁₀H₂₀O
Cas No.	1490-04-6
Smiles	CC(C)C1CCC(C)CC1O
Relative Density.	0.904 at 59° F (NTP, 1992)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (319.98 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.3996 mL	31.9980 mL	63.9959 mL	319.9795 mL
5 mM	1.2799 mL	6.3996 mL	12.7992 mL	63.9959 mL
10 mM	0.6400 mL	3.1998 mL	6.3996 mL	31.9980 mL
20 mM	0.3200 mL	1.5999 mL	3.1998 mL	15.9990 mL
50 mM	0.1280 mL	0.6400 mL	1.2799 mL	6.3996 mL
100 mM	0.0640 mL	0.3200 mL	0.6400 mL	3.1998 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

MentholCalciumChannelCalcium Channel

Related Tags: Menthol chemical structure | Menthol in vivo | Menthol formula | Menthol molecular weight