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Cholesteryl oleate [303-43-5]

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Référence NB-64-09121-50mg

Conditionnement : 50mg

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Cholesteryl oleate

(Synonyms: Oleoylcholesterol, Cholesteryl cis-9-octadecenoate, Cholesterol Oleate) Copy Product Info

Synonyms: Oleoylcholesterol, Cholesteryl cis-9-octadecenoate, Cholesterol Oleate

Catalog No. T19237 Copy Product Info

Purity: 99.24%

Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach.

Cas No. 303-43-5

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.24%

Appearance:Viscous

Color:Transparent

Product Introduction

Cholesteryl oleate AI Summary

Cholesteryl oleate exhibits significant antibacterial activity against a variety of bacteria, including Streptococcus mutans, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella Typhimurium, and Escherichia coli. Additionally, it demonstrates robust antifungal activity against Candida albicans, Candida krusei, Candida parapsilosis, and Cryptococcus neoformans. The compound’s bioactivity is confirmed by its inhibition of microorganism growth, as evidenced by the inhibition zone (IZ) and minimum inhibitory concentration (MIC) values reported in different assays..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) is a cholesteryl ester. Cholesteryl oleate can be used to synthesize solid lipid nanoparticles which is a nanoparticle-based gene therapy approach.
Synonyms	Oleoylcholesterol, Cholesteryl cis-9-octadecenoate, Cholesterol Oleate

Chemical Properties

Molecular Weight	651.1
Formula	C₄₅H₇₈O₂
Cas No.	303-43-5
Smiles	CCCCCCCC\C=C/CCCCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCCC(C)C
Relative Density.	0.9287 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Acetone: 45 mg/mL (69.11 mM), Sonication is recommended.

DMSO: 5 mg/mL (7.68 mM), Sonication is recommended.

Ethanol: 10 mg/mL (15.36 mM), Sonication and heating to 50℃ are recommended.

Solution Preparation Table

DMSO/Ethanol/Acetone

	1mg	5mg	10mg	50mg
1 mM	1.5359 mL	7.6793 mL	15.3586 mL	76.7931 mL
5 mM	0.3072 mL	1.5359 mL	3.0717 mL	15.3586 mL

Ethanol/Acetone

	1mg	5mg	10mg	50mg
10 mM	0.1536 mL	0.7679 mL	1.5359 mL	7.6793 mL

Acetone

	1mg	5mg	10mg	50mg
20 mM	0.0768 mL	0.3840 mL	0.7679 mL	3.8397 mL
50 mM	0.0307 mL	0.1536 mL	0.3072 mL	1.5359 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

InhibitorinhibitHuman Endogenous MetaboliteEndogenousMetaboliteEndogenous MetaboliteCholesteryl oleate

Related Tags: Cholesteryl oleate chemical structure | Cholesteryl oleate formula | Cholesteryl oleate molecular weight