General Information
| Short Description | Mouse monoclonal anti-F-box-like/WD repeat-containing protein TBL1XR1 for use in WB, IHC and IF in Human, Mouse, Rat, Cow, Chicken, Dog, Pig and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat/Cow/Chicken/Dog/Pig/Zebrafish |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity purification |
| Dilution Range | WB 1:1000-1:2000IHC 1:500-1:1000IF 1:100-1:500 |
| Formulation | Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Purified recombinant human TBL1XR1 protein fragments expressed in E.coli. |
| Specificity | TBL1XR1 Monoclonal Antibody detects endogenous levels of TBL1XR1 protein. |
Additional Info
| Function | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. |
| Protein Name | F-Box-Like/Wd Repeat-Containing Protein Tbl1xr1Nuclear Receptor Corepressor/Hdac3 Complex Subunit Tblr1Tbl1-Related Protein 1Transducin Beta-Like 1x-Related Protein 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-F-Box-Like/Wd Repeat-Containing Protein Tbl1xr1 antibodyAnti-Nuclear Receptor Corepressor/Hdac3 Complex Subunit Tblr1 antibodyAnti-Tbl1-Related Protein 1 antibodyAnti-Transducin Beta-Like 1x-Related Protein 1 antibodyAnti-TBL1XR1 antibodyAnti-IRA1 antibodyAnti-TBLR1 antibody |
Information sourced from Uniprot.org