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> Anti-BMP4 Antibody (8X974)

Anti-BMP4 Antibody (8X974)

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Référence NB-64-153129-50uL

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Anti-BMP4 Monoclonal Antibody (8X974)

(Synonyms: DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4, BMP4, BMP-2B, BMP2B) Copy Product Info

Synonyms: DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4, BMP4, BMP-2B, BMP2B

Catalog No. TMAB-03164 Copy Product Info
Anti-BMP4 Monoclonal Antibody (8X974) is a Rabbit antibody targeting BMP4. Anti-BMP4 Monoclonal Antibody (8X974) can be used in WB,IHC-P,ICC/IF,FCM,IP.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Description
Anti-BMP4 Monoclonal Antibody (8X974) is a Rabbit antibody targeting BMP4. Anti-BMP4 Monoclonal Antibody (8X974) can be used in WB,IHC-P,ICC/IF,FCM,IP.
SynonymsDVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4, BMP4, BMP-2B, BMP2B
Ig Type
IgG
Clone
8X974
Reactivity
Human
Application
WB
IHC-P
ICC/IF
FCM
IP
Recommended Dose
WB: 1:1000-1:5000; IHC: 1:100-1:200; ICC/IF: 1:200-1:500; FCM: 1:100-1:500; IP: 1:10-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Monoclonal Antibody
PurificationAffinity Purified
AppearanceLiquid
Formulation50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA
Research BackgroundBone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation. BMPs belongs to the TGF-β superfamily, playing many diverse functions during development. BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Synthetic peptide of human BMP4
Antigen Species
Human
Gene Name
BMP4
Gene ID
652
Protein Name
Bone morphogenetic protein 4
Uniprot ID
P12644
Biology Area
Cardiovascular
Chemical Properties
Molecular WeightCalculated MW: 47 kDa; Observed MW: 47 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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