Anti-Phospho-IGF1R/CD221 (Tyr1165, 1166) Polyclonal Antibody

Application

IF

WB

Antibody TypeHost SpeciesRabbitConstructionPolyclonal AntibodyPurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.AppearanceLiquidFormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Research BackgroundThis receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	Phospho

Antigen Details

Immunogen	Peptide sequence around phosphorylation site of tyrosine 1165/tyrosine 1166 (T-D-Y(p)-Y(p)-R-K) derived from Human IGF-1R
Antigen Species	human
Uniprot ID	P08069

Chemical PropertiesStability & Storage

Stability & Storage	Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.