Testosterone buciclate [118931-19-4]

Referencia NB-64-26275-50mg

embalaje : 50mg

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Testosterone buciclate

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Synonyms:

Catalog No. T38572 Copy Product Info
Testosterone buciclate, a long-acting androgen ester, shows promise as a research agent for male hypogonadism.
Cas No. 118931-19-4
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Description
Testosterone buciclate, a long-acting androgen ester, shows promise as a research agent for male hypogonadism.
In vivo
Testosterone buciclate, administered intramuscularly (i.m.) at four different sites with 20 mg per site on the first and ninety-first days of a 360-day study period, demonstrates a decreased testicular volume between days 90 and 270, and significantly reduces sperm motility and gel penetrability, except on day 120, during days 45 to 240. It also leads to a reduction in sperm count from day 75 to 270 and increases the percentage of spermatozoa exhibiting cytoplasmic droplet retention and coiled tails, with the exception of day 120, throughout days 45 to 240[1].
Chemical Properties
Molecular Weight454.695
FormulaC30H46O3
Cas No.118931-19-4
SmilesCCCCC1CCC(CC1)C(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |t:21|
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Keywords

Testosterone buciclate
Related Tags: Testosterone buciclate chemical structure | Testosterone buciclate in vivo | Testosterone buciclate formula | Testosterone buciclate molecular weight