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> IL-2 Protein, Rat, Recombinant (His)

IL-2 Protein, Rat, Recombinant (His)

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IL-2 Protein, Rat, Recombinant (His)

(Synonyms: TCGF, T-cell growth factor, Interleukin-2, IL-2, IL2, Aldesleukin) Copy Product Info

Synonyms: TCGF, T-cell growth factor, Interleukin-2, IL-2, IL2, Aldesleukin

Catalog No. TMPJ-00877 Copy Product Info
Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Other Forms of IL-2 Protein, Rat, Recombinant (His):
IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Mouse, Recombinant (His & Avi)
IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL-2 Protein, Human, Recombinant (E. coli)
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)
IL-2 Protein, Rabbit, Recombinant (His)
IL-2 Protein, Rat, Recombinant
IL-2 Protein, Canine, Recombinant (C147S)
IL-2 Protein, Mouse, Recombinant
IL-2 Protein, Human, Recombinant (His)
IL-2 Protein, Human, Recombinant
For research use only—not for human use. No sales to individuals. Use as intended only.
Select Batch
Purity:SDS-PAGE: 95.1%; SEC-HPLC: 93.1%
Appearance:Solution
Contact us for more batch information

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Species
Rat
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberP17108
Amino AcidAla21-Gln155
ConstructionAla21-Gln155
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 5 mM NaH<sub>2</sub>PO<sub>4</sub>, 5 mM Citric acid, 150 mM NaCl, pH 4.0.
SynonymsTCGF, T-cell growth factor, Interleukin-2, IL-2, IL2, Aldesleukin
Research Background
Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Chemical Properties
Molecular Weight14-16 KDa (reducing condition)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

IL 2
Related Tags: IL-2 Protein, Rat, Recombinant (His) chemical structure | IL-2 Protein, Rat, Recombinant (His) molecular weight