General Information
| Short Description | Goat polyclonal Choroideremia (Rab escort protein 2) antibody for use in WB in human, mouse, rat, bovine, canine, chicken, avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep and simian samples. Datasheet included with dil |
| Applications | WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 3 mg/mL |
| Purification | This antibody is epitope-affinity purified from goat antiserum. |
| Dilution Range | WB 1:500-1:5000 |
| Formulation | PBS, 20% Glycerol and 0.05% Sodium Azide. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Accession Number | ENSG00000203668 |
| Immunogen | Purified recombinant human TNF alpha produced in E. coli. |
| Immunogen Sequence | IIFDGDDKQPEAPGTNNVVM IFDGDDKQPEAPGTNNVVMA FDGDDKQPEAPGTNNVVMAK |
| Specificity | Detects endogenous REP2 by Western blot. This Ab is specific for REP2, it does not cross-react with REP1. |
Additional Info
| Function | Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. |
| Protein Name | Rab Proteins Geranylgeranyltransferase Component A 2Choroideremia-Like ProteinRab Escort Protein 2Rep-2 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Rab Proteins Geranylgeranyltransferase Component A 2 antibodyAnti-Choroideremia-Like Protein antibodyAnti-Rab Escort Protein 2 antibodyAnti-Rep-2 antibodyAnti-CHML antibodyAnti-REP2 antibody |
Information sourced from Uniprot.org