IL-2 Protein, Human, Recombinant (E. coli)

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Katalog-Nummer NB-64-53755-20ug

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IL-2 Protein, Human, Recombinant (E. coli)

(Synonyms: TCGF, T-Cell Growth Factor, Interleukin-2, IL-2, IL2, Aldesleukin) Copy Product Info

Synonyms: TCGF, T-Cell Growth Factor, Interleukin-2, IL-2, IL2, Aldesleukin

Catalog No. TMPJ-01463 Copy Product Info
IL-2 Protein, Human, Recombinant (E. coli) is expressed in E. coli expression system. The accession number is P60568.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
1. Loaded Human IL-2RA-Fc on Protein A Biosensor, can bind Human IL-2 with an affinity constant of 17.0 nM as determined in BLI assay. (Regularly tested) 2. Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The specific activity of Recombinant Human IL-2 is ≥1×10^7 IU/mg. (QC verified)
Description
IL-2 Protein, Human, Recombinant (E. coli) is expressed in E. coli expression system. The accession number is P60568.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberP60568
Amino AcidAla21-Thr153
ConstructionAla21-Thr153
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
IL-2 Protein, Human, Recombinant (E. coli)
Endotoxin< 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 10 mM sodium citrate, pH 4.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTCGF, T-Cell Growth Factor, Interleukin-2, IL-2, IL2, Aldesleukin
Research Background
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

IL 2
Related Tags: IL-2 Protein, Human, Recombinant (E. coli) chemical structure