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> Fas Ligand Protein, Mouse, Recombinant (His)

Fas Ligand Protein, Mouse, Recombinant (His)

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Katalog-Nummer NB-64-59623-100ug

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Fas Ligand Protein, Mouse, Recombinant (His)

(Synonyms: Tnfsf6, gld, Faslg, Fas-L, Fasl, Fas ligand, CD95-L, Cd95l, CD178, Apt1lg1) Copy Product Info

Synonyms: Tnfsf6, gld, Faslg, Fas-L, Fasl, Fas ligand, CD95-L, Cd95l, CD178, Apt1lg1

Catalog No. TMPY-04587 Copy Product Info
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 18.2 kDa and the accession number is AAB02915.1.
Other Forms of Fas Ligand Protein, Mouse, Recombinant (His):
Fas Ligand Protein, Human, Recombinant (His)TMPY-03956
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 90 % as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 18.2 kDa and the accession number is AAB02915.1.
Species
Mouse
Expression System
P. pastoris (Yeast)
TagN-His
Accession NumberAAB02915.1
ConstructionA DNA sequence encoding the mouse Faslg (AAB02915.1) (Pro132-Leu279) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity
> 90 % as determined by SDS-PAGE.
EndotoxinPlease contact us for more information.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsTnfsf6, gld, Faslg, Fas-L, Fasl, Fas ligand, CD95-L, Cd95l, CD178, Apt1lg1
Research Background
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Chemical Properties
Molecular Weight18.2 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

CD-178CD 178
Related Tags: Fas Ligand Protein, Mouse, Recombinant (His) chemical structure | Fas Ligand Protein, Mouse, Recombinant (His) molecular weight