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> POU5F1 Protein, Human, Recombinant (B2M & His)

POU5F1 Protein, Human, Recombinant (B2M & His)

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POU5F1 Protein, Human, Recombinant (B2M & His)

(Synonyms: transcription factor 1, POU5F1, POU domain, class 5, transcription factor 1, OTF3, Octamer-binding transcription factor 3 (OTF-3), Octamer-binding protein 4 (Oct-4), Octamer-binding protein 3 (Oct-3), class 5) Copy Product Info

Synonyms: transcription factor 1, POU5F1, POU domain, class 5, transcription factor 1, OTF3, Octamer-binding transcription factor 3 (OTF-3), Octamer-binding protein 4 (Oct-4), Octamer-binding protein 3 (Oct-3), class 5

Catalog No. TMPH-01895 Copy Product Info
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. POU5F1 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 52.6 kDa and the accession number is Q01860.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. POU5F1 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 52.6 kDa and the accession number is Q01860.
Species
Human
Expression System
E. coli
TagN-6xHis-B2M
Accession NumberQ01860
Amino AcidMAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
Construction1-360 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonymstranscription factor 1, POU5F1, POU domain, class 5, transcription factor 1, OTF3, Octamer-binding transcription factor 3 (OTF-3), Octamer-binding protein 4 (Oct-4), Octamer-binding protein 3 (Oct-3), class 5
Research Background
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Chemical Properties
Molecular Weight52.6 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

POU5F 1OTF-3OTF 3class54593445933
Related Tags: POU5F1 Protein, Human, Recombinant (B2M & His) chemical structure | POU5F1 Protein, Human, Recombinant (B2M & His) molecular weight