Size : 50mg
Telefonnummer : +1 850 650 7790
Synonyms:
| Description | MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues, producing a positively charged side chain similar in size to lysine. |
| In vitro | Activation by Cd is occluded by modification with 2-aminoethyl MTS (MTSEA), indicating that Cd binds directly and specifically to the substituted cysteines.?Cd potency for the A657C mutation (EC50 = 10 M) suggests that binding involves at least two coordinating residues, whereas weaker Cd potency for L659C (EC50 = 2 mM) implies that activation does not require tight coordination by multiple side chains for this substitution.Cys modification by MTSEA reduces susceptibility to Cd activation of receptors with A8C or L10C substitutions[1]. |
| Molecular Weight | 236.15 |
| Formula | C3H10BrNO2S2 |
| Cas No. | 16599-33-0 |
| Smiles | Br.O=S(=O)(SCCN)C |
| Relative Density. | 1.31g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
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