Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie

Impurity C of Calcitriol [86307-44-0]

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Katalog-Nummer NB-64-02953-25mg

Size : 25mg

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Telefonnummer : +1 850 650 7790

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Impurity C of Calcitriol

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Synonyms:

Catalog No. T11645 Copy Product Info

Impurity C of Calcitriol is an impurity of Calcitriol.Impurity C of Calcitriol is used in the synthesis of vitamin D3.

Cas No. 86307-44-0

For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

Product Introduction

Bioactivity

Description	Impurity C of Calcitriol is an impurity of Calcitriol.Impurity C of Calcitriol is used in the synthesis of vitamin D3.
In vitro	Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol) inhibits cell proliferation in a wide range of cells including breast, prostate, colon, skin, and brain carcinomas and myeloid leukemia cells.

Chemical Properties

Molecular Weight	591.78
Formula	C₃₅H₄₉N₃O₅
Cas No.	86307-44-0
Smiles	21[C@@]1(CC[C@@]2(21)C3=C[C@@H](C4=C(C)[C@@H](O)C[C@H](O)C4)n4n(c(=O)n(-c5ccccc5)c4=O)[C@]3(21)CC[C@]12C)[C@H](C)CCCC(C)(C)O
Relative Density.	1.27 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (76.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6898 mL	8.4491 mL	16.8982 mL	84.4909 mL
5 mM	0.3380 mL	1.6898 mL	3.3796 mL	16.8982 mL
10 mM	0.1690 mL	0.8449 mL	1.6898 mL	8.4491 mL
20 mM	0.0845 mL	0.4225 mL	0.8449 mL	4.2245 mL
50 mM	0.0338 mL	0.1690 mL	0.3380 mL	1.6898 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Keywords

VDImpurity C of Calcitriol

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