Antiviral agent 73

Katalog-Nummer NB-64-144999-10mg

Size : 10mg

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Antiviral agent 73

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Catalog No. T214179 Copy Product Info
Antiviralagent 73 (compound D13) is a potent inhibitor of intercellular movement with antiviral activity. It inactivates the Potato virus Y (PVY) with an EC50 value of 79.5 μg/mL. By forming stable hydrogen bonds with the Pro154 of the PVY coat protein, Antiviralagent 73 effectively hinders viral infection. Additionally, it disrupts Pro154-mediated intercellular viral transport through plasmodesmata. Antiviralagent 73 is applicable for the prevention and control of plant viruses.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Description
Antiviralagent 73 (compound D13) is a potent inhibitor of intercellular movement with antiviral activity. It inactivates the Potato virus Y (PVY) with an EC50 value of 79.5 μg/mL. By forming stable hydrogen bonds with the Pro154 of the PVY coat protein, Antiviralagent 73 effectively hinders viral infection. Additionally, it disrupts Pro154-mediated intercellular viral transport through plasmodesmata. Antiviralagent 73 is applicable for the prevention and control of plant viruses.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 µL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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